Graphline Systems is a founder-led engineering firm. We build custom software, make infrastructure reliable, and help teams put AI to work, with deep roots in biotech and agentic, knowledge-graph systems.
Before
Manual & Reactive
Issues in spreadsheets. No visibility. Slow response times.
Your team waits on analysis and pipelines instead of doing the science.
Deployments need tribal knowledge, and only one person can run them.
You want to put AI to work, but can’t separate the real wins from the hype.
Critical knowledge lives in people’s heads and walks out the door.
Infrastructure costs keep climbing while reliability keeps slipping.
You need senior engineering leadership, but not a full-time CTO yet.
Production-grade pipelines, notebooks, and experiment tracking that give small biotech teams the computational-biology infrastructure they need on day one, without hiring a DevOps engineer.
A single, access-partitioned brain that AI agents run on, self-hosted and model-independent. Benchmarked at full-context accuracy on roughly a tenth of the tokens, with cost that stays flat as the corpus grows.
An internal scientific analysis platform re-architected from fragile research code into a production system: automated testing, CI/CD, autoscaling compute, SSO, and end-to-end observability.
Custom software architecture and delivery of an agentic library system with a shared-memory layer for incubators and their resident companies.
When off-the-shelf tools fall short, we design and build custom platforms, internal tools, and integrations, including AI-enabled and agentic workflows and knowledge-graph systems that keep institutional knowledge usable.
Research software that does not scale, fragile analysis pipelines, risky deployments, and engineers afraid to touch the system. We turn scientific platforms into scalable, observable, production-grade systems, with deep roots in biotech and life sciences.
We help teams improve reliability, automate operations, reduce incidents, and build infrastructure that scales with the business.
When you need technical leadership, architecture oversight, and an AI strategy grounded in reality, but are not ready for a full-time executive hire.
Architecture, scalability, security, and engineering assessments for investors, acquirers, and leadership teams.
Graphline Systems is a software and infrastructure firm in the SF Bay Area. We build custom software, make infrastructure reliable, and help teams put AI to work, with deep roots in biotech, agentic systems, and knowledge graphs.
Founder Brent Mills has spent seventeen years in production engineering, from early-stage startups through Wayfair’s ~4,000-engineer org. He led platform and SRE teams of up to 32 engineers at Wayfair, restored Nursa’s application uptime from 84% to 99.97%, and stood up the SRE function at IBM Resilient across HIPAA, ISO 27001, and GDPR regulated environments.
Start with a 15-minute intro call, or send an email. We’ll talk through where your systems are today and what it would take to make them reliable.
Pick a time that works and it’s booked: a quick call to see whether we’re the right fit for what you’re building.
Pick a timePrefer email? Send a note about your team and systems and we’ll get back to you, usually the same day.
brent@graphline-systems.com Send an email